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Interestingly, the TREM2 hi macrophage (foam cell) population was implicated in the clonal expansion of effector CD4 + T cells in atherosclerotic lesions mediated via multiple pathways associated with costimulation and immunological synapse formation
doi:10.1042/bj2860929
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The Nrf2-Keap1 defence pathway: role in protection against drug-induced toxicity
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However, as [Cys] rises an increasing fraction is sent towards the synthesis of taurine
