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A variety of compounds in alkaloid families have shown multiple therapeutic effects, for example, their antitumor, antimicrobial, anti-inflammatory and antidiabetic properties (Wu et al., 2018)

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A normal RBC does not rule out a need for B12 supplementation

This is a critical error, as macrocytosis typically only appears in the final stage, when it may already be too late

Thus a beef was born

(i) A deficiency of the enzyme cystathionine beta-synthase (CBS) , methylenetetrahydrofolate reductase (MTHFR) , and methionine synthase (MS) results in the accumulation of homocysteine