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Others have linked low glutathione levels to lack of sleep in animals and in people with certain sleep disorders

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Absorption into the CNS after intranasal administration has been postulated to occur via the olfactory and trigeminal neuronal pathways (intraneuronal) and diffusion across mucosal barrier and olfactory plate (extraneuronal), depending on the size, polarity, and odorant nature

Hepatocyte-specificGclc deletion leads to rapid onset of steatosis with mitochondrial injury and liver failure

The primary role of NAC as an antioxidant stems from its ability to increase the intracellular concentration of glutathione (GSH), which is the most crucial biothiol responsible for cellular redox imbalance

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