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It also lowers triglycerides and cholesterol levels, which can enhance heart health

[8] Similarly, patients with gout or hyperuricemia should avoid high niacin intake, as niacin (even in nicotinamide form) can raise uric acid levels and potentially trigger gout flares

This is not an issue with an injection (since IM/IV bypasses the gut), but if a patient is also taking oral supplements, they should separate them from tetracycline dosing
5-Amino-1MQ is a synthetic small-molecule compound classified as an NNMT (nicotinamide N-methyltransferase) inhibitor

Its not so much about sterility, but about photolysis destruction by light

This is consistent with studies showing that HA can improve the performance of nanoparticle-based drug formulations by extending local retention and reducing systemic absorption [1]