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The function of white adipose tissue is often impaired in obese and diabetic individuals, resulting in adipocyte hypertrophy, pathological fat accumulation, and ectopic fat deposition, which can lead to the development of metabolic and cardiovascular diseases

Bioaccumulation heightens its toxicity during critical developmental periods, potentially causing congenital cardiac defects, endocrine disorders, and other pathological changes

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doi: 10.1016/j.addr.2012.10.007

Una carencia de esta vitamina provoca un trastorno madurativo de los precursores mieloides, y debilitar y alterar la mielina debido al aumento de los niveles de cido metilmalnico