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Epigenetic modifications by histone deacetylases: Biological implications and therapeutic potential in liver fibrosis

The penthouse certainly helps with the latter

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The current combination of uncertain benefit and uncertain product integrity warrants a cautious and structured clinical approach

[DOI] [PMC free article] [PubMed] [Google Scholar] 164.Paun A, Yau C, Danska JS

Calcium flowing into the spine through NMDA receptors binds to the Ca 2+ -binding protein calmodulin (CaM), and the Ca 2+ -CaM complex then activates the holoenzyme CaMKII that is necessary and sufficient for LTP induction (Lisman et al., 2012)