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In a molecular docking assay, it was further found that EGCG directly binds to the mouse KEAP1 protein by forming hydrogen bonds with specific residues within the KEAP1 protein, suggesting that NRF2 may play a key role in the protection of DN by EGCG through inhibition of the function of the KEAP1 protein
In diabetic models, Caveolin-1 expression is significantly reduced
The chemistry of nitrosative stress induced by nitric oxide and reactive nitrogen oxide species
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Sequencing results were analyzed using the ContigExpress software (Thermo Fisher Scientific), and compared with the NCBI database ( for H
