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doi: 10.1016/j.exger.2021.111476 235 SonnevilleR.BenghanemS.JeantinL.de MontmollinE.DomanM.GaudemerA.et al

The Nrf2 regulatory network provides an interface between redox and intermediary metabolism

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There are several mechanisms which may underlie the association between type II diabetes and dementia, including neurotoxicity resulting from hyperglycemia, alterations in amyloid metabolism, increased risk of cerebrovascular disease, and a combination of these mechanisms (6)

CYP24A1 is responsible for the catabolic inactivation of 25(OH)VD and 1,25(OH) 2 D, which helps regulate 1,25(OH) 2 D signaling [19]

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