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The case of rasburicase (urate oxidase) This drug, licensed about 10 years ago for the prohpylaxis and treatment of hyperuricaemia associated with tumour lysis syndrome (TLS), deserves special attention for several reasons

Activity modification during treatment is essential for optimal results

With consistent use, many users report noticeable improvements in skins texture and visible reduction in stretch mark depth within weeks

Inhibiting RB protein in vivo promotes the efficacy of sorafenib, and RB protein can be used as an indicator of sorafenib sensitivity (Louandre et al., 2015)

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