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Clinical and observational data indicate that the COVID-19 mRNA products may predispose individuals to these adverse outcomes within a three-year post-injection window, with persistent synthetic spike protein complicating clearance assumptions

The PL-10 trial (a phase 2 study for inflammatory bowel disease) was listed on registries but full peer-reviewed results were not published

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doi: 10.1016/j.clim.2016.10.019 116 HerriotRMiedzybrodzkaZ

These typically resolve with continued use and may relate to changes in sleep architecture as the body adjusts