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In relation to the bone, IGF-1 is an important mediator of the effects of GH and modulates bone growth through its paracrine action in the growth plate (220) as it was demonstrated that the selective deletion of the igf1 gene in the liver and a consequent decrease in systemic IGF-1 did not affect the animals body and femoral growth (221)

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glabrata has a well defined oxidative stress response (OSR), which include both enzymatic and non-enzymatic mechanisms

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Principles of synaptic organization of GABAergic interneurons in the striatum