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In the ConA-induced murine model of AIH, the upregulation of IDO1 is closely associated with liver injury, an increase in reactive nitrogen species (RNS), and the promotion of ferroptosis [220]

[DOI] [PMC free article] [PubMed] [Google Scholar] 56.Kuloglu M, Atmaca M, Tezcan E, et al

These are all manifestations of the havoc wreaked by free radicals
