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doi: 10.1007/s00011-021-01509-3 67 WangXChengWChenXGongYWangGZhangXet al

Cholesterol metabolic reprogramming occurs in the TME during the functional maturation and activation of TILs

However, while the majority of patients carrying AIFM1 mutations exhibit clear signatures of impaired mitochondrial bioenergetics and other metabolic defects (e.g., lactic acidosis), clinical outcomes greatly vary among patients with regard to phenotypic expressivity and tissue specificity 8

Efficacy of B-cell targeted therapy with rituximab in patients with active moderate to severe Graves orbitopathy: a randomized controlled study

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