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Consistent with this finding, we observed higher expression of TGF and p-Smad2 in NP and L929 cocultures, but no expression of either was observed in NP and 293T cocultures (Supplementary Fig

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Now, cuprizone is commonly administered for 46 weeks to study acute demyelination or up to 12 weeks to study chronic demyelination, and mice are occasionally followed after cuprizone withdrawal to study remyelination (Fig

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