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Nephron 1991;57(3):306-313

however, recent research suggests that mitochondrial dysfunction (MDF) may contribute to DILI

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[19,20] Differential diagnosis has also been recommended in other toxic states where ALAD activity is suppressed such as zinc deficiency, smoking, alcoholism, diabetes mellitus and chronic renal insufficiency

doi: 10.1038/srep20391

we used a random-effect model and a profound improvement in LVEF was observed in patients who received L-C therapy (WMD: 4.14%, 95% CI: 2.34 to 5.93, P = 0.01, Figure 5(a))
