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Larsson SC, Woolf B, Gill D (2023) Appraisal of the causal effect of plasma caffeine on adiposity, type 2 diabetes, and cardiovascular disease: two sample mendelian randomisation study

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The paper established MOTS-c as an "exercise mimetic" and launched the field of mitochondrial-derived peptide research (Lee C et al., Cell Metab

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A 2025 study published in the Proceedings of the National Academy of Sciences (PNAS) highlighted that patients with post-viral dysautonomia and ME/CFS often exhibit markedly abnormal levels of plasma carnitine and free fatty acids