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6, HPRT1 may therefore warrant further study as a potential alternative target for pharmacological induction to achieve similar treatment effects as the combination of inosine and XDH inhibition

Intestinal barrier dysfunction in NAFLD Intestinal structural barrier impairment and consequent inflammation in NAFLD Diet-induced elevation of systemic LPS levels, termed metabolic endotoxemia, is a key driver in the pathogenesis of chronic metabolic disorders, including obesity, type 2 diabetes, and NAFLD

M.BurgessS.et al (2021)

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doi: 10.12998/wjcc.v10.i30.11122 201 Semler-ColleryAHayekGRamadierSPeroneJ-M

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