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Gastroenterology 2021;160:15701583.ArticlePubMed 12

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PloS Negl Trop Dis (2015) 8:e0003998

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The signaling pathways of synaptic dysfunction The main signaling pathways involved in synaptic dysfunction include phosphatidylinositol 3kinase/Protein kinase B/Mammmalian target of rapamycin (PI3K/Akt/mTOR) signal and abnormal autophagy, extracellular signalregulated kinase/mitogenactivated protein kinase (ERK/MAPK) signal, Janus kinase and microtubule interacting protein 1 (JAKMIP1) pathway, and calcium signaling

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