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Methods In this study, we design a two-in-one ferroptosis-inducing nanoplatform using iron-based metal-organic framework (MOF) that combines iron supply and GPX4 deactivation by loading the small molecule buthionine sulfoxide amine (BSO) to block de novo GSH biosynthesis, which can achieve sustainable GSH elimination and dual ferroptosis amplification
Surgery has proved to be effective for several pNPs

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While the body produces some L-Carnitine on its own, supplementation can be beneficial, especially for those engaged in regular physical activity or following specific dietary regimes