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Type 1 ribotoxin-curcin conjugated biogenic gold nanoparticles for a multimodal therapeutic approach towards brain cancer

The treatment group showed lower mortality than controls, and no significant adverse effects were reported

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As can be seen, the results of different studies demonstrate the efficacy of c-Met targeting

This antitumorigenic effect is mediated through the activation of cyclin-dependent kinase inhibitors specifically p21 & p27, which disrupt the action of mitogenic growth factors such as insulin-like growth factor 1 (IGF-1) and epidermal growth factor (EGF), while simultaneously enhancing the tumour-suppressive effects of transforming growth factor-beta (TGF-)

It is not intended for human consumption or for use in therapeutic, diagnostic, or clinical settings