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53 Low B 12 concentrations in the body may be present in different pathophysiological situations, including pregnancy, old age, smoking, and comorbidities such as hypertension, diabetes mellitus, pancreatic insufficiency, autoimmune gastritis, gastrectomy or gastric bypass, diseases or resection of the ileum, bacterial overgrowth, celiac disease, inflammatory bowel disease, or uremia-related malnutrition

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While dietary sources such as meat, seafood, and animal products typically provide sufficient Vitamin B12, some individualsespecially those with dietary restrictions or absorption issuesmay experience deficiencies

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In diet-induced obese models, it produced a 7-10% reduction in body weight in just 11 days by increasing the basal metabolic rate