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Additionally, statins and liver X receptor antagonists suppress cholesterol biosynthesis and reduce mevalonate availability, thereby preventing mTOR-mediated trained immunity (96, 187)
Romes NB, Abdul Wahab R, Abdul HM
Berberine represses human gastric cancer cell growth in vitro and in vivo by inducing cytostatic autophagy via inhibition of MAPK/mTOR/p70S6K and Akt signaling pathways
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This imbalance promotes the generation of reactive oxygen species (ROS), which in turn drives lipid peroxidation (von Krusenstiern et al., 2023)
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