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Distribution of the ghrelin receptor In rat tissues, the ghrelin receptor is abundantly expressed in the hypothalamic arcuate nucleus, a key center for feeding regulation (Korbonits et al., 2004

E., Gladyshev, V

Viral proteins containing the purine NTP-binding sequence pattern

p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death

Cytotoxicity screening of Cu 3 -TC-Py and Cu 3 -TC-Thio showed Cu 3 -TC-Py to be a substantially more potent agent with a clear ability to internalise intracellular Cu ions when monitored via ICP-MS

Thus, the signaling mechanisms of drug-induced cell death involving ROS and peroxynitrite are flexible and can change depending on susceptibility (e.g., PUFA levels in membranes) and impairment of multi-layered antioxidant defense systems
