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In mice, ASCT2 deficiency impairs the induction of T H 1 and T H 17 cells, due to a defect of glutamine uptake and mTORC1 activation (Nakaya et al , 2014)

Melatonin Protects against Neuronal Damage Induced by 3-Nitropropionic Acid in Rat Striatum

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In addition to iron uptake, after crossing the outer membrane, zinc uptake is facilitated by a periplasmic binding protein and a homologous membrane permease system ZnuABC (also called MntABC in the literature), and mutants unable to produce any of these proteins are defective in intracellular survival (Lim et al., 2008)

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This is why B12 deficiency is taken seriously