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Gastrointestinal side effects like nausea, vomiting, and diarrhea can cause fluid loss, which temporarily elevates creatinine and makes kidney function look worse than it is
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As demonstrated by Dvila-Gonzlez and coworkers, NOS II inhibition, coupled to a constant expression of NOS III, sensitized TNBC cells to docetaxel and activated the ER stress-dependent pro-apoptotic transducers such as CHOP [49]
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