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Luteolin suppresses this pathway by preventing phosphorylation and degradation of the inhibitory protein IB, thereby blocking nuclear translocation of NF-B p65 and reducing transcription of pro-inflammatory cytokines (TNF-, IL-1, IL-6), iNOS, COX-2, and adhesion molecules (Khan et al., 2024)

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The combined treatment induced immunological memory, as mice that underwent tumor-regression were resistant to re-challenge with the same tumor (116)

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10.1002/adhm.202403933 113 XuH.YangL.WuY.LeiH

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Obesity, 23(11), 2165-2174

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References American Psychiatric Association (2013) Diagnostic and statistical manual of mental disorders, fifth edition (DSM-5)

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This was accompanied by an increase in the labelling of glucose transporters GLUT1 and GLUT3 suggesting an increase in uptake of metabolites (87)

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