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And, remember, that the antibodies you get from having had the disease are usually gone within 3 months after having had it.

Given the therapeutic hypotheses associated with NNMT, selective, potent, and cell-active inhibitors would be a valuable tool for assessing its therapeutic potential

However, the tests employing both 14 Carbon or 13 Carbon labeled cobalamin require more validation to diagnose B12 malabsorption in clinical patients (Miller & Green, 2020)

Theoretical concerns exist for individuals with active cancer due to angiogenic properties, though research hasn't identified increased cancer risk

Gene 2001

In asymptomatic patients with risk factors (see Table 1: Patient Risk Factors Associated with B 12 Deficiency below) consider supplementation in lieu of testing