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Formononetin as promising therapeutic intervention for restoring ovarian, uterine, and Hepato-renal functions in letrozole-induced, polycystic ovarian syndrome Sprague Dawley rats

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NO is beneficial in normal conditions, but when it reacts with superoxide (O ), it produces peroxynitrite, which can be harmful

Fedorowski et al., 2017

DNA methylation takes place in CpG dinucleotides, by the addition of a methyl group on the position 5 of the cytosine pyrimidine ring

*Severe primary IGF-1 deficiency (IGFD) is defined by height standard deviation score -3.0 and basal IGF-1 standard deviation score -3.0 and normal or elevated GH