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Semba, K

They are a rich source of growth factors

Frequent Administration : Diabetic patients requiring 3-4 daily insulin injections, hemophiliacs needing clotting factor replacement, dialysis patients with repeated punctures must prioritize long-term comfort and vascular preservationselect finest possible needle sizes combined with injection site rotation strategies

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Loehrer FMT, Haefeli WE, Angst CP, Browne G, Frick G, and Fowler B (1996)

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