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Beyond mycoses, BDG has been shown to induce long-term epigenetic reprogramming, reverse LPS-induced tolerization in monocytes/macrophages, and confer protection from infectious diseases including leishmaniasis and tuberculosis (1214)

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10.1126/science.1172638 85 TakeshitaJ.GrewalS.LanganS

These findings are consistent with those for other antioxidant enzymes: for example, lack of peroxiredoxin 3, a mitochondrially localized antioxidant enzyme, also augments apoptotic signaling in some cell types (60)