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Mack, D

Effects of 5-azacytidine and butyrate on differentiation and apoptosis of hepatic cancer cell lines

doi: 10.3389/fnut.2021.765809 Summary Keywords combination therapy, glutamine metabolism, immune microenvironment, metabolic reprogramming, tumors Citation Fang L, Gao D, Jiang Z, Li G and Li M (2025) Glutamines double-edged sword: fueling tumor growth and offering therapeutic hope
Main active ingredients and mechanism of action are as given (all are GLP-1 agonist): All have similar mechanism of action by mimicking the natural hormone GLP-1, it increases insulin secretion when blood sugar is high, suppresses the release of glucagon (a hormone that raises blood sugar), and slows the emptying of the stomach

Extracellular vesicle-packaged circTAX1BP1 from cancer-associated fibroblasts regulates RNA m6A modification through lactylation of VIRMA in colorectal cancer cells