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For injured tissue that is poorly supplied with blood, this effect may be particularly relevant

Before any injection

Recent medical insights have reinforced the role of systemic inflammation and insulin resistance in exacerbating lipid imbalances

Nature 590 , 382384 (2021)

They diverge in molecular stability, required administration route, mechanistic depth (particularly the beta3-adrenergic data for AOD-9604), and the weight of clinical evidence behind each
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doi: 10.1007/s10787-025-02035-y, 80
