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We put forward the hypothesis of ferroptosis, a recently identified iron-dependent cell death, as a potential underlying mechanism of BD

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Despite prior concerns regarding potential adverse effects, a 23-h fasting regimen mitigates metabolic abnormalities observed in Pcca-mutated mice by reducing propionate production from the microbiome and  enhancing propionyl-CoA disposal for gluconeogenesis and fatty acid oxidation to acetyl-CoA.