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[DOI] [PMC free article] [PubMed] [Google Scholar] 128.Fang X., Han H., Li M., Liang C., Fan Z., Aaseth J., He J., Montgomery S., Cao Y

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These proteins play a role in cellular repair and antioxidant defence, leading to mitigated lung resilience, thus leading to severe respiratory conditions such as asthma, pulmonary fibrosis and COPD (Park et al

When considering the biological effects of IGF1 in second primary lung cancer, it has been shown that lung mesenchymal cells locally synthesize IGF1 which acts on the bronchial epithelium in a paracrine manner 56