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Secondary outcome measurements included reduction in body weight from baseline by at least 5% or 10% by week 26, changes in waist circumference, total cholesterol, HDL, LDL, VLDL, and triglycerides, and levels of different glycemic variables including HbA1C, fasting plasma glucose, fasting insulin, insulin resistance, and the functioning of beta-cells

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This was shown when a group of mice had improved symptoms of Metabolic Syndrome (MetS) including better regulation of glucose, triglycerides, and cholesterol levels after being given IGF-1.: Insulin growth factor 1 (IGF-1) has multiple effects on metabolism

According to the ATS, indications include atypical clinical presentation and/or chest radiographic findings, complications of lung disease (e.g., malignancy), and clinical implication of disease with normal chest radiographic findings