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Aging involves DNA damage, mitochondrial decline, hormonal shifts, and cellular senescence all at once

They are not regulated by the FDA for human consumption, which means there is no oversight on purity, potency, contamination, or dosing accuracy

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Horne BD, Muhlestein JB, Lappe DL, May HT, Carlquist JF, Galenko O et al (2013) Randomized cross-over trial of short-term water-only fasting
during labor or cesarean delivery, or for pain control after abdominal surgery)