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In the Sibutramine Cardiovascular Outcomes (SCOUT) trial, the drug was shown to be associated with increased risk of major adverse cardiovascular events (a composite of non-fatal heart attack, non-fatal stroke, resuscitation after cardiac arrest, and cardiovascular death) in obese patients, as compared to placebo [29]

This decline can impair physical function and mobility

Rapid response to prevent and treat B12/Co deficiency

It accelerates the breakdown of existing fat stores and prevents new fat from forming, regardless of caloric intake

Gordon CM, Ackerman KE, Berga SL, Kaplan JR, Mastorakos G, Misra M, et al
