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Furthermore, despite the use of NAC, some patients may still experience persistent phlegm symptoms

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Apart from increased intracellular iron load, ferroptosis is also characterized by excessive lipid peroxidation and reduced expression and function of antioxidant defense genes, particularly glutathione peroxidase 4 (Gpx4) and system Xc(Xct) [11]

Evid Based Complem Altern Med 2020(1):8091047 Frema Amanfo A et al (2023) Anticataract effect of the aqueous extract of the flowers of Aspilia africana in murine model of diabetic and age-related cataracts

In contrast to Trx1, incubation of Grx1 with 0.5 mM MQ resulted in 4 adducts and 1 mM MQ was needed for modification of all 5 thiols (Supplementary Fig