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[DOI] [PMC free article] [PubMed] [Google Scholar] 182.Pagoni A., Arvaniti O.S., Kalantzi O.-I

Then -catenin binds to a protein called TrCP (beta-transducin repeat containing protein) that mediates the ubiquitination of CTNNB1 and the proteins tagged with ubiquitin are degraded by the proteosome that results in -catenin destruction by the proteosomal degradation

3 Family history and genetic susceptibility The genetic susceptibility plays a critical role in the pathogenesis of both lung cancer and hypertension

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