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After 3 days of incubation on NGM plates the overall levels of reduced thiols and GSH became lower in DB (Fig

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Iron deposition leads to hyperphosphorylation of Tau and disruption of insulin signaling

Technical and biological hurdles are paramount, including the inefficient delivery of cells or vectors to widespread motor neurons across the central nervous system, host immune responses that can limit efficacy or durability, and unresolved long-term safety concerns such as off-target effects or uncontrolled cell differentiation (15, 60, 65)
[DOI] [PubMed] [Google Scholar] 196.Trauelsen, M