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SIRT2 H187Y (an enzyme dead mutant) OE did not reduce the lactylation of USP2 under TGF1 stimulation, while WT SIRT2 OE remarkably decreased the lactylation level of USP2 (Fig

They found that epithalamin led to a median lifespan extension of between 14% and 32% longer than control subjects

For example, PCS isolated from plant species can accept -alkylated GSH such as -methyl-GS and -hexyl-GS [6, 95] and large side residues like xenobiotic GS-conjugates (abbreviated as GS-conjugates) [17, 19, 20]

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[PMC free article: PMC3151424] [PubMed: 21473702] 407