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Yes it is widely used and studied across South and Southeast Asian skin tones, which tend to have higher melanin levels

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The substituents R, R, R and R may be independently selected from hydrogen, substituted or unsubstituted alkyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted heterocycloalkyl, substituted or unsubstituted aryl, and substituted or unsubstituted heteroaryl

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Besides bipolar I and II, other subtypes include fast cycling (more than four manic, depressive, hypomanic, or mixed episodes in one year) and cyclothymia (hypomanic and subdepressive symptoms over two years) [43]

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Aducanumab: First Approval

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Patients receiving anti-TNF therapies experience clinically important improvements in RA-related fatigue: results from the British Society for Rheumatology Biologics Register for Rheumatoid Arthritis

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