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Furthermore, TMAO-treated cardiomyocytes also revealed the build-up of glycogen and lipofuscin-like pigment, suggesting a mitochondrial dysfunction and lower ATP production that affects the contractile function of cardiomyocytes

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Rac1 activation in podocytes induces rapid foot process effacement and proteinuria Mol Cell Biol 33 23: 4755-64

Source: NIH Office of Dietary Supplements [1]

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