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Klionsky, Saeid Ghavami Seminars in Cancer Biology.2024

Papait R., Serio S., Condorelli G., Physiol

N(1)H- and N(1)-Substituted phenylguanidines as 7 nicotinic acetylcholine (nACh) receptor antagonists: Structure-Activity relationship studies
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In besonderen Fllen von schlecht heilenden Wunden wie Verbrennungen, Erfrierungen oder Gangrn-Ulzera kommt auch die Applikation in Form von Salben, Spray oder als Flssigkeit in Frage und fhrt zu guten therapeutischen Ergebnissen.In special cases of poorly healing wounds such as burns, frostbite or gangrene ulcers, application in the form of ointments, spray or as a liquid can also be considered and leads to good therapeutic results

doi: 10.1089/ars.2010.3587

This delivery process is driven by the formation of transient persulfide on the active cysteine of NFS1, which forms a complex with ISD11 (also known as LYRM4) and the mitochondrial acyl carrier protein (ACP) [44]
