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10.1186/1476-4598-10-117 283 YangC.ChenY.LiF.YouM.ZhongL.LiW.et al (2018)

The neuroprotective effects come through multiple pathways: inhibition of nitric oxide synthesis under ischemic conditions, antioxidant activity, protection against glutamate neurotoxicity, and mitochondrial stabilization under calcium dysregulation

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The peptides oral bioavailabilityunique among healing peptidesmakes it an ideal therapeutic agent for digestive disorders

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Together, these findings suggest that Semas ability to engage central appetite-regulating networksparticularly in the hypothalamus, brainstem, and reward centersmakes it a valuable compound for ongoing research into obesity, energy regulation, and neuroendocrine control of eating behavior
