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In this review, we discuss the alterations of gut microbiome and its metabolites in NIU and outline the potential mechanisms linking these changes to the disease

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Molecular mechanisms of quinone cytotoxicity

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The addition of equimolar or higher concentrations of Cu 2+ to Htt induces oligomerization, along with the rapid reduction of Cu 2+ to Cu 1+ (Neupane et al., 2025)