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Gut Microbiota and Coronary Artery Disease: Current Therapeutic Perspectives

Ultra-performance liquid chromatography-tandem mass spectrometry (UPLCMS/MS) UPLCMS/MS performed on a Waters Acquity UPLC-Xevo TQ-S UPLCMS/MS system equipped with an Acquity BEH HILIC (2.1 100 mm, 1.7 m) chromatographic column was employed to determine TMA, TMAO, choline, betaine, -butyrobetaine, betaine aldehyde, butyryl-carnitine, isovaleryl-carnitine, OH-isovaleryl-carnitine, stearoyl-carnitine, oleoyl-carnitine, linoleoyl-carnitine, myristoyl-carnitine, lauroyl-carnitine, and decanoyl-carnitine as described previously 31,41

Moras D, Billas IM, Rochel N, Klaholz BP

The Green-Med diet also impacted biological age, as assessed by DNA methylation age clocks

In addition, a metabolomics approach identified higher concentrations of long-chain acylcarnitines in incident dialysis patients, and these high concentrations were a marker of cardiovascular mortality after multivariable adjustment [15]

however, in more advanced disease with greater blood flow restriction, symptoms are more persistent