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1c, except it used either WT AGO2 (left panel) or a variant with mutations in the PAZ-domain pocket (F294A, Y311A) (right panel), and it used target RNAs with varying internal loops lengths (panel a ) (Supplementary Table 1)

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274,275 1,2-Dioleyloxy-3-dimethylaminopropane (DODMA) and its analog 1,2-dioleyloxy-3-(dimethylamino) propane (DODAP) were among the first ILs used for RNA delivery

P.ChandaS.GanjuL.SinghS

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