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Liu B, Wang H
This bidirectional, stable axis connects the gut with the central nervous system
This upregulation results in a substantial accumulation of intracellular Fe2+, causing tissue damage (127)
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PMID: 30074168
(2018) reported that removal of these cells in INK-ATTAC transgenic mice prevents gliosis, reduced tau hyperphosphorylation in both soluble and insoluble forms, impeded neurofibrillary tangle formation, and prevented cortical and hippocampal neurodegeneration, thus preserving cognitive function
