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134 Mutant IDH-targeted therapy and a number of important recent pre-clinical and clinical studies in IDH-mutant solid tumors have been extensively reviewed elsewhere, 147 and listed in Table 2

However, this contrasts to the scenario after consumption of an overdose of APAP where the sulfation pathway is saturated7, and NAPQI generation is significantly elevated in spite of the high capacity of the glucuronidation pathway9

Calabro, S

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doi: 10.1007/s11136-018-1842-3

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